Process Development for Purification of Therapeutic Antisense Oligonucleotides by Anion-Exchange Chromatography
- 29 March 2000
- journal article
- review article
- Published by American Chemical Society (ACS) in Organic Process Research & Development
- Vol. 4 (3), 205-213
- https://doi.org/10.1021/op990091o
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Application of sample displacement techniques to the purification of synthetic oligonucleotides and nucleic acids: a mini-review with experimental resultsJournal of Chromatography A, 1998
- Selectivity of anion exchange chromatography and capillary gel electrophoresis for the analysis of phosphorothioate oligonucleotidesJournal of Pharmaceutical and Biomedical Analysis, 1997
- Gram-scale purification of phosphorothioate oligonucleotides using ion-exchange displacement chromatographyNucleic Acids Research, 1995
- Quantitative capillary gel electrophoresis assay of phosphorothioate oligonucleotides in pharmaceutical formulationsJournal of Chromatography A, 1994
- Separation of synthetic phosphorothioate oligodeoxynucleotides from their oxygenated (phosphodiester) defect species by strong-anion-exchange high-performance liquid chromatographyJournal of Chromatography A, 1992
- Ion-exchange high-performance liquid chromatography analysis of oligodeoxyribonucleotide phosphorothioatesAnalytical Biochemistry, 1992
- A general method for the purification of synthetic oligodeoxyribonucleotides containing strong secondary structure by reversed-phase high-performance liquid chromatography on PRP-1 resinAnalytical Biochemistry, 1987
- High-performance anion-exchange chromatography of oligonucleotidesAnalytical Biochemistry, 1985
- A Simplified Procedure for the Analytical Extraction of LipidsScience, 1949