Distribution ofemmgenotypes among group A streptococcus isolates from patients with severe invasive streptococcal infections in Japan, 2001–2005
- 9 February 2007
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 135 (7), 1227-1229
- https://doi.org/10.1017/s0950268807007984
Abstract
SUMMARY: We surveyedemmgenotypes of group A streptococcus (GAS) isolates from patients with severe invasive streptococcal infections during 2001–2005 and compared their prevalence with that of the preceding 5 years. Genotypeemm1remained dominant throughout 2001 to 2005, but the frequency rate of this type decreased compared with the earlier period. Various otheremmtypes have appeared in recent years indicating alterations in the prevalent strains causing severe invasive streptococcal infections. The cover of the new 26-valent GAS vaccine fell from 93·5% for genotypes of isolates from 1996–2000 to 81·8% in 2001–2005.Keywords
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