Rapamycin partially prevents insulin resistance induced by chronic insulin treatment
- 10 May 2002
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 293 (3), 1021-1027
- https://doi.org/10.1016/s0006-291x(02)00333-9
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Insulin-stimulated Protein Kinase B Phosphorylation on Ser-473 Is Independent of Its Activity and Occurs through a Staurosporine-insensitive KinasePublished by Elsevier BV ,2001
- Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase ControlPublished by Elsevier BV ,2001
- Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in VivoPublished by Elsevier BV ,2000
- PKB Inhibition Prevents the Stimulatory Effect of Insulin on Glucose Transport and Protein Translocation but Not the Antilipolytic Effect in Rat AdipocytesBiochemical and Biophysical Research Communications, 2000
- β3-Adrenergic Stimulation Differentially Inhibits Insulin Signaling and Decreases Insulin-induced Glucose Uptake in Brown AdipocytesPublished by Elsevier BV ,1999
- Development of Insulin Resistance in 3T3-L1 AdipocytesJournal of Biological Chemistry, 1997
- The Pleckstrin Homology Domain Is the Principle Link between the Insulin Receptor and IRS-1Published by Elsevier BV ,1996
- Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.JCI Insight, 1995
- The Insulin Receptor Substrate (IRS-1) Is a Pest Protein That Is Susceptible to Calpain Degradation in VitroBiochemical and Biophysical Research Communications, 1993
- Insulin Stimulates the Degradation of IRS-1 in 3T3-L1 AdipocytesBiochemical and Biophysical Research Communications, 1993