Sequencing nucleic acids: from chemistry to medicine
- 4 May 2011
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 47 (26), 7281-7286
- https://doi.org/10.1039/c1cc11078k
Abstract
Chemistry has played a vital role in making routine, affordable sequencing of human genomes a reality. This article focuses on the genesis and development of Solexa sequencing that originated in Cambridge, UK. This sequencing approach is helping transform science and offers intriguing prospects for the future of medicine.Keywords
This publication has 22 references indexed in Scilit:
- Next-generation DNA sequencingNature Biotechnology, 2008
- Finishing the euchromatic sequence of the human genomeNature, 2004
- Probing DNA Surface Attachment and Local Environment Using Single Molecule SpectroscopyThe Journal of Physical Chemistry B, 2001
- Solid phase DNA amplification: characterisation of primer attachment and amplification mechanismsNucleic Acids Research, 2000
- Optically Biased Diffusion of Single Molecules Studied by Confocal Fluorescence MicroscopyThe Journal of Physical Chemistry B, 1998
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences of the United States of America, 1977
- A new method for sequencing DNA.Proceedings of the National Academy of Sciences of the United States of America, 1977
- Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic AcidNature, 1953
- 13. Nucleotides. Part X. Some observations on the structure and chemical behaviour of the nucleic acidsJournal of the Chemical Society, 1952
- Über neue organische Phosphorverbindungen III. Phosphinmethylenderivate und PhosphinimineHelvetica Chimica Acta, 1919