Treponema denticola and Porphyromonas gingivalis as Prognostic Markers Following Periodontal Treatment
- 1 April 1992
- journal article
- Published by Wiley in The Journal of Periodontology
- Vol. 63 (4), 270-273
- https://doi.org/10.1902/jop.1992.63.4.270
Abstract
Subgingival plaque samples were collected from individuals with advanced periodontitis before and 3 to 11 weeks after scaling and root planing periodontal treatment. The plaque levels of Treponema denticola and Porphyromonas gingivalis antigens were measured before and after treatment by a quantitative immunoassay procedure using monoclonal antibodies specific for these oral bacteria. A decrease in mean levels of T. denticola (P <.05) and P. gingivalis antigens (P <. 09) were observed following periodontal therapy. Improved health, as measured by a decrease in probing depth, was associated with a decrease in T. denticola antigen (P <.05). These results suggest that the T. denticola levels of successfully treated sites decreased, while non-responding sites had levels of this microbial marker which were equal to or greater than the pre-treatment levels. These results provide additional evidence that T. denticola is associated with human adult severe periodontal disease, and can serve as a prognostic marker ...Keywords
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