α-Secretase-Derived Cleavage of Cellular Prion Yields Biologically Active Catabolites with Distinct Functions
- 17 January 2012
- journal article
- review article
- Published by S. Karger AG in Neurodegenerative Diseases
- Vol. 10 (1-4), 294-297
- https://doi.org/10.1159/000333804
Abstract
The cellular prion protein (PrPc) undergoes α-secretase-derived processing by disintegrins. This cleavage occurs within the 106–126 putative toxic domain of PrPc, yielding two coThis publication has 25 references indexed in Scilit:
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