Phthalazinone in Heterocyclic Synthesis: Synthesis of Some s-Triazole, s-Triazolothiadiazine, s-Triazolothiadiazine, and s-Triazolothiadiazole Derivatives as Pharmaceutical Interest
- 1 September 2003
- journal article
- research article
- Published by Taylor & Francis Ltd in Phosphorus, Sulfur, and Silicon and the Related Elements
- Vol. 178 (9), 1987-1997
- https://doi.org/10.1080/10426500390228666
Abstract
1(2H)-Oxophthalazine-2-acetic acid ethyl ester was allowed to react with various reagents under different conditions to yield compounds 2-[(4-substituted-5-mercaptotriazol-3-yl) methyl]-1 (2H)-oxophthalzines 5 and 7 which acted as starting materials for the preparation of some new s-triazolo[5,1-b][1,3]thiazine (8), s-triazolo[3,4-b][1,3,4]thiadiazine 9,12,14,20, and s-triazolo[3,4-b][1,3,4]thiadiazole 18,21 derivatives.Keywords
This publication has 14 references indexed in Scilit:
- Synthesis and Reaction of Some Indenopyridine and Thieno[2,3-b]Indeno[2,1-e]Pyridine DerivativesSynthetic Communications, 2000
- Studies on condensed heterocyclic compounds II. Synthesis and antibacterial activity of 3-(4′-pyridyl)-6-aroylamino/arylamino-S-triazolo[3,4-b]-1,3,4-thiadiazolesChinese Journal of Chemistry, 1992
- Synthesis and biological activity of bridgehead nitrogen heterocyclesJournal of Heterocyclic Chemistry, 1986
- Ring closure reactions involving 1-hydrazinophthalazine. Reactions with 1,2,4-tricarbonyl and 1,3-dicarbonyl compoundsJournal of Heterocyclic Chemistry, 1983
- Improved syntheses of 5‐substituted‐4‐amino‐3‐mercapto‐(4H)‐1,2,4‐triazolesJournal of Heterocyclic Chemistry, 1976
- Synthesis of some s-triazoles with potential analgesic and antiinflammatory activitiesJournal of Medicinal Chemistry, 1971
- Potential antidiabetics. 7. N1-(.beta.-hydroxybenzylmethyl)-3-methyl-4-arylhydrazono-2-pyrazolin-5-ones and N1-(.beta.-hydroxybenzylmethyl)-3-methyl-4-arylazo-5-methyl- or -phenylpyrazolesJournal of Medicinal Chemistry, 1971
- Pyridazin-derivate. V. Synthese der Derivate des 6-Phenyl-3 (2H)-pyridazinons.CHEMICAL & PHARMACEUTICAL BULLETIN, 1964
- 276. Aryl-2-halogenoalkylamines. Part XVI. The preparation of derivatives of 4-[di-(2-chloroalkyl)amino]azobenzenesJournal of the Chemical Society, 1956
- Some Further Studies on Tuberculostatic CompoundsJournal of Pharmacy and Pharmacology, 1952