Recent progress in understanding hydrophobic interactions
- 24 October 2006
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences of the United States of America
- Vol. 103 (43), 15739-15746
- https://doi.org/10.1073/pnas.0606422103
Abstract
We present here a brief review of direct force measurements between hydrophobic surfaces in aqueous solutions. For almost 70 years, researchers have attempted to understand the hydrophobic effect (the low solubility of hydrophobic solutes in water) and the hydrophobic interaction or force (the unusually strong attraction of hydrophobic surfaces and groups in water). After many years of research into how hydrophobic interactions affect the thermodynamic properties of processes such as micelle formation (self-assembly) and protein folding, the results of direct force measurements between macroscopic surfaces began to appear in the 1980s. Reported ranges of the attraction between variously prepared hydrophobic surfaces in water grew from the initially reported value of 80-100 Angstrom to values as large as 3,000 Angstrom. Recent improved surface preparation techniques and the combination of surface force apparatus measurements with atomic force microscopy imaging have made it possible to explain the long-range part of this interaction (at separations >200 Angstrom) that is observed between certain surfaces. We tentatively conclude that only the short-range part of the attraction (<100 Angstrom) represents the true hydrophobic interaction, although a quantitative explanation for this interaction will require additional research. Although our force-measuring technique did not allow collection of reliable data at separations <10 Angstrom, it is clear that some stronger force must act in this regime if the measured interaction energy curve is to extrapolate to the measured adhesion energy as the surface separation approaches zero (i.e., as the surfaces come into molecular contact).Keywords
This publication has 115 references indexed in Scilit:
- Interfaces and the driving force of hydrophobic assemblyNature, 2005
- Forces Measured between Latex Spheres in Aqueous Electrolyte: Non-DLVO Behavior and Sensitivity to Dissolved GasLangmuir, 1999
- Study of the Long-Range Hydrophobic Attraction in Concentrated Salt Solutions and Its Implications for Electrostatic ModelsLangmuir, 1998
- Is the long-range hydrophobic attraction related to the mobility of hydrophobic surface groups?Colloids and Surfaces A: Physicochemical and Engineering Aspects, 1997
- Long-Range Electrostatic Attraction between Similar, Charge-Neutral WallsPhysical Review Letters, 1995
- Effect of Dissolved Gas and Salt on the Hydrophobic Force between Polypropylene SurfacesLangmuir, 1994
- Hydrophobic attraction: a reexamination of electrolyte effectsThe Journal of Physical Chemistry, 1992
- Electrostatic correlation forces between surfaces with surface specific ionic interactionsThe Journal of Chemical Physics, 1989
- Forces between fluorocarbon surfactant monolayers: salt effects on the hydrophobic interactionThe Journal of Physical Chemistry, 1989
- Very long range attractive forces between uncharged hydrocarbon and fluorocarbon surfaces in waterThe Journal of Physical Chemistry, 1988