Manioc Flour Consumption as a Risk Factor for Lead Poisoning in the Brazilian Amazon
- 28 January 2013
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Toxicology and Environmental Health, Part A
- Vol. 76 (3), 206-216
- https://doi.org/10.1080/15287394.2013.752326
Abstract
Recent studies reported elevated blood lead (Pb) levels in riparian populations of the Amazon. For this reason, the aim of the present study was to assess the risk to riparians in the Brazilian Amazon to Pb exposure due to the intake of contaminated manioc flour. Lead levels were determined in whole blood (n = 74) and in manioc flour samples (n = 30) in three different communities. Mean blood Pb levels were 16.8 μg/dl, with individuals living in Açaituba presenting the highest mean blood Pb level (22.4 μg/dl), followed by Nova Canaã (17.3 μg/dl) and Santa Cruz (9.8 μg/dl). The minimum blood Pb level found was 0.83 μg/dl and the maximum was 44.3 μg/dl. The estimated daily intake (EDI) was calculated and compared to the benchmark dose lower confidence limit (BMDL) for neurotoxicity. Mean Pb in manioc flour was 0.34 μg/g while EDI was 79 μg/d, corresponding to 260% of the BMDL (varying from 168 to 308%). This finding is of great importance since this high EDI may exert adverse effects on the nervous system of this population. Manioc flour intake may thus present considerable risk of Pb exposure in this region. Risk management strategies and further studies on adverse effects in this population are needed.This publication has 34 references indexed in Scilit:
- Assessment of Immunotoxicity Parameters in Individuals Occupationally Exposed to LeadJournal of Toxicology and Environmental Health, Part A, 2012
- Lead exposure in indigenous communities of the Amazon basin, PeruInternational Journal of Hygiene and Environmental Health, 2011
- Environmental Lead Exposure and Otoacoustic Emissions in Andean ChildrenJournal of Toxicology and Environmental Health, Part A, 2011
- Risk assessment of the lead intake by consumption of red deer and wild boar meat in Southern SpainFood Additives & Contaminants: Part A, 2011
- Neurophysiologic and Neurocognitive Case Profiles of Andean Patients with Chronic Environmental Lead PoisoningJournal of Toxicology and Environmental Health, Part A, 2009
- Lead toxicity, vulnerable subpopulations and emergency preparednessRadiation Protection Dosimetry, 2009
- Dietary exposure to antimony, lead and mercury of secondary school students in Hong KongFood Additives & Contaminants: Part A, 2008
- Lead Concentration in the Blood of Children and its Association with Lead in Soil and Ambient Air—Trends Between 1983 and 2000 in DuisburgJournal of Toxicology and Environmental Health, Part A, 2008
- Toxic trace metal speciation: importance and tools for environmental and biological analysisPure and Applied Chemistry, 1998
- Renal effects of environmental and occupational lead exposure.Environmental Health Perspectives, 1997