Increased Activation of Hereditary Pancreatitis-associated Human Cationic Trypsinogen Mutants in Presence of Chymotrypsin C
Open Access
- 1 June 2012
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 287 (24), 20701-20710
- https://doi.org/10.1074/jbc.m112.360065
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Asparagine-linked glycosylation of human chymotrypsin C is required for folding and secretion but not for enzyme activityThe FEBS Journal, 2011
- Chymotrypsin C mutations in chronic pancreatitisJournal of Gastroenterology and Hepatology, 2011
- High Affinity Small Protein Inhibitors of Human Chymotrypsin C (CTRC) Selected by Phage Display Reveal Unusual Preference for P4′ Acidic ResiduesJournal of Biological Chemistry, 2011
- Intragenic DuplicationPancreas, 2011
- Expression of Recombinant Proteins with Uniform N-TerminiPublished by Springer Science and Business Media LLC ,2010
- Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanismHuman Mutation, 2009
- The Guinea Pig Pancreas Secretes a Single Trypsinogen Isoform, Which Is Defective in AutoactivationPancreas, 2008
- Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitisNature Genetics, 2007
- Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme YProceedings of the National Academy of Sciences, 2007
- Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitisHuman Mutation, 2006