Immunostimulating hexapeptide from human casein: amino acid sequence, synthesis and biological properties
Open Access
- 1 December 1984
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 145 (3), 677-682
- https://doi.org/10.1111/j.1432-1033.1984.tb08609.x
Abstract
A hexapeptide obtained from human casein by enzymatic digestion has been purified, sequenced and synthesized; its structure is: Val‐Glu‐Pro‐Ile‐Pro‐Tyr. In vitro this hexapeptide stimulates the phagocytosis of opsonized sheep red blood cells by murine peritoneal macrophages. Administered intravenously to adult mice, it enhances the resistance to infection with Klebsiella pneumoniae.This publication has 20 references indexed in Scilit:
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