oPOSSUM-3: Advanced Analysis of Regulatory Motif Over-Representation Across Genes or ChIP-Seq Datasets
Open Access
- 1 September 2012
- journal article
- Published by Oxford University Press (OUP) in G3 Genes|Genomes|Genetics
- Vol. 2 (9), 987-1002
- https://doi.org/10.1534/g3.112.003202
Abstract
OPOSSUM-3 is a web-accessible software system for identification of over-represented transcription factor binding sites (TFBS) and TFBS families in either DNA sequences of co-expressed genes or sequences generated from high-throughput methods, such as ChIP-Seq. Validation of the system with known sets of co-regulated genes and published ChIP-Seq data demonstrates the capacity for oPOSSUM-3 to identify mediating transcription factors (TF) for co-regulated genes or co-recovered sequences. oPOSSUM-3 is available at http://opossum.cisreg.ca.This publication has 41 references indexed in Scilit:
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