Risk of infection in patients with lymphoma receiving rituximab: systematic review and meta-analysis
Open Access
- 12 April 2011
- journal article
- review article
- Published by Springer Science and Business Media LLC in BMC Medicine
- Vol. 9 (1), 36
- https://doi.org/10.1186/1741-7015-9-36
Abstract
The addition of Rituximab (R) to standard chemotherapy (C) has been reported to improve the end of treatment outcome in patients affected by CD-20 positive malignant lymphomas (CD20+ ML). Nevertheless, given the profound and prolonged immunosuppression produced by R there are concerns that severe infections may arise. A systematic review and meta-analysis were performed to determine whether or not the addition of R to C may increase the risk of severe infections in adults undergoing induction therapy for CD20+ ML.This publication has 40 references indexed in Scilit:
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