Influenza virus genome consists of eight distinct RNA species.
- 1 September 1976
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences of the United States of America
- Vol. 73 (9), 3045-3049
- https://doi.org/10.1073/pnas.73.9.3045
Abstract
The genomic RNA of the avian influenza A virus, fowl plague, was fractionated into eight species by electrophoresis in polyacrylamide-agarose gels containing 6 M urea. The separated 32P-labeled RNA species were characterized by digestion with RNase T1 and fractionation of the resulting oligonucleotides by two-dimensional gel electrophoresis; this demonstrated that each species has a distinct nucleotide sequence. A tentative correlation of each genome RNA species with the virus protein that it encodes was made.Keywords
This publication has 21 references indexed in Scilit:
- Influenza viral messenger RNAVirology, 1974
- Studies on the formation of the influenza virus envelopeVirology, 1974
- Association of influenza virus proteins with cytoplasmic fractionsVirology, 1974
- Mechanism of influenza recombinationVirology, 1973
- Influenza virus proteinsVirology, 1973
- Distinct oligonucleotide patterns of distinct influenza virus RNA'sJournal of Molecular Biology, 1972
- Estimations of the Molecular Weight of the Influenza Virus GenomeJournal of General Virology, 1971
- Molecular weights of ribosomal RNA in relation to evolutionJournal of Molecular Biology, 1968
- Genetic Recombination with Newcastle Disease Virus, Polioviruses, and InfluenzaPublished by Cold Spring Harbor Laboratory ,1962
- Structure of Influenza VirusScience, 1956