Adult Weight Change and Risk of Postmenopausal Breast Cancer
Open Access
- 12 July 2006
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 296 (2), 193-201
- https://doi.org/10.1001/jama.296.2.193
Abstract
Obesity is associated with many chronic diseases, including cancer, and postmenopausal breast cancer in particular.1,2 Weight loss is associated with several short-term benefits, such as improvements in lipid levels, blood pressure, and blood glucose metabolism,3 but thus far there has been little evidence of longer-term effects on cancer risk.4 Postmenopausal weight loss lowers circulating estrogens,5 and given that these hormones are directly related to the risk of breast cancer,6-8 weight loss is suspected to decrease risk. However, this has not been consistently shown.Keywords
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