HIF-2α Promotes Hypoxic Cell Proliferation by Enhancing c-Myc Transcriptional Activity
Top Cited Papers
Open Access
- 10 April 2007
- journal article
- Published by Elsevier BV in Cancer Cell
- Vol. 11 (4), 335-347
- https://doi.org/10.1016/j.ccr.2007.02.006
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysisGenes & Development, 2007
- Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotypeCancer Cell, 2006
- The phosphorylation status of PAS-B distinguishes HIF-1α from HIF-2α in NBS1 repressionThe EMBO Journal, 2006
- Loss of Tumor Suppressor p53 Decreases PTEN Expression and Enhances Signaling Pathways Leading to Activation of Activator Protein 1 and Nuclear Factor κB Induced by UV RadiationCancer Research, 2005
- Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell CarcinomaMolecular and Cellular Biology, 2005
- Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor GrowthPLoS Biology, 2003
- Hypoxia Inducible Factor Activates the Transforming Growth Factor-α/Epidermal Growth Factor Receptor Growth Stimulatory Pathway in VHL-/- Renal Cell Carcinoma CellsOnline Journal of Public Health Informatics, 2003
- Regulation of angiogenesis by hypoxia: role of the HIF systemNature Medicine, 2003
- p21Cip1 and p27Kip1Regulate Cell Cycle Reentry after Hypoxic Stress but Are Not Necessary for Hypoxia-Induced ArrestMolecular and Cellular Biology, 2001
- Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1αGenes & Development, 1998