Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Abstract

Non-epithelial malignancies of the ovary account for ∼10% of all ovarian cancers [1]. Germ cell tumors (GCTs) are diagnosed principally in the first two decades of life, whereas sex cord-stromal tumors (SCSTs) are more common in adult women (granulosa adult type has an average age at diagnosis of 50 years, 90% of juvenile type occurs in pre-pubertal girls and Sertoli-Leydig occurs mainly in women younger than 40 years). The yearly adjusted incidence rate is 3.7/1 000 000 and 2.1/1 000 000 women for GCTs and SCSTs, respectively [2].