Current Management of Locally Advanced Junction Esophagogastric Adenocarcinoma
- 1 January 2018
- journal article
- review article
- Published by Celsius Publishing House in Chirurgia
- Vol. 113 (1), 38-45
- https://doi.org/10.21614/chirurgia.113.1.38
Abstract
Adenocarcinoma of the gastroesophageal junction is more common in the West. Preoperative chemotherapy or chemoradiotherapy is performed for locally advanced disease. Recent studies are suggesting higher rates of curative resection and reduced rates of local recurrence in patients with neoadjuvant combination of chemotherapy and radiation therapy. The role of targeted agents in neoadjuvant therapy is under investigation.Keywords
This publication has 32 references indexed in Scilit:
- Preoperative treatment of locally advanced esophageal carcinomaInternational Journal of Oncology, 2013
- Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicentre, phase 2/3 randomised trialThe Lancet Oncology, 2013
- Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: Systematic review with meta-analysis combining individual patient and aggregate dataEuropean Journal of Cancer, 2013
- Hospital volume, proportion resected and mortality from oesophageal and gastric cancer: a population-based study in England, 2004–2008Gut, 2012
- Highlights of the EORTC St. Gallen International Expert Consensus on the primary therapy of gastric, gastroesophageal and oesophageal cancer – Differential treatment strategies for subtypes of early gastroesophageal cancerEuropean Journal of Cancer, 2012
- A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targetsGut, 2012
- Diagnosis and treatment of non-metastatic esophagogastric junction adenocarcinoma: What are the current options?Journal of Visceral Surgery, 2012
- Esophageal cancer: definitive chemoradiotherapy for elderly patientsDiseases of the Esophagus, 2010
- Phase III Comparison of Preoperative Chemotherapy Compared With Chemoradiotherapy in Patients With Locally Advanced Adenocarcinoma of the Esophagogastric JunctionJournal of Clinical Oncology, 2009
- Epidemiology of upper gastrointestinal malignanciesSeminars in Oncology, 2004