Retropharyngeal and Bowel Hematomas in an Anticoagulated Patient
- 1 January 1994
- journal article
- case report
- Published by Wiley in Academic Emergency Medicine
- Vol. 1 (1), 67-72
- https://doi.org/10.1111/j.1553-2712.1994.tb02804.x
Abstract
As the indications for oral anticoagulation therapy increase, the number of patients being treated with anticoagulants and at risk for complications also will rise. Major bleeding episodes have been reported to occur in approximately 2-4% of patients being treated with oral anticoagulants. The case report of a patient with concurrent spontaneous retropharyngeal and small-bowel hematomas from overanticoagulation with warfarin is presented. The authors review the subtle presentation of retropharyngeal hematomas, common medications that may enhance warfarin anticoagulation, and therapy of potentially life-threatening hematomas. Airway management and possible surgical therapies to treat the complications of hematomas are discussed. Depending upon the indication for the initial anticoagulation, interim anticoagulation with heparin may be indicated.Keywords
This publication has 26 references indexed in Scilit:
- Warfarin in the Prevention of Stroke Associated with Nonrheumatic Atrial FibrillationThe New England Journal of Medicine, 1992
- The Effect of Warfarin on Mortality and Reinfarction after Myocardial InfarctionThe New England Journal of Medicine, 1990
- Trial of Different Intensities of Anticoagulation in Patients with Prosthetic Heart ValvesThe New England Journal of Medicine, 1990
- Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapyThe American Journal of Medicine, 1989
- Is the dose of warfarin prescribed by American physicians unnecessarily high?Archives of Internal Medicine, 1987
- Bleeding during acetylsalicylic acid and anticoagulant therapy in patients with reduced platelet reactivity after aortic valve replacementAmerican Heart Journal, 1980
- Stereoselective Interaction of Trimethoprim-Sulfamethoxazole with the Separated Enantiomorphs of Racemic Warfarin in ManThe New England Journal of Medicine, 1980
- Upper airway obstruction as a complication of oral anticoagulation therapy. Report of three casesArchives of Internal Medicine, 1979
- Pharmacokinetic parameters estimated from intravenous data by uniform methods and some of their usesJournal of Pharmacokinetics and Biopharmaceutics, 1977
- Retropharyngeal Hematoma: A Complication of Therapy With AnticoagulantsJAMA Otolaryngology–Head & Neck Surgery, 1975