Necrotizing Enterocolitis in the Premature Infant
- 1 June 2011
- journal article
- beyond the-basics
- Published by Ovid Technologies (Wolters Kluwer Health) in Advances in Neonatal Care
- Vol. 11 (3), 155-164
- https://doi.org/10.1097/anc.0b013e31821baaf4
Abstract
Necrotizing enterocolitis (NEC) remains one of the most catastrophic comorbidities associated with prematurity. In spite of extensive research, the disease remains unsolved. The aims of this article are to present the current state of the science on the pathogenesis of NEC, summarize the clinical presentation and severity staging of the disease, and highlight the nursing assessments required for early identification of NEC and ongoing care for infants diagnosed with this gastrointestinal disease. The distributions of systemic and intestinal clinical signs that are most sensitive to nursing assessment and associated with Bell Staging Criteria are presented. These descriptive data are representative of 117 cases of NEC diagnosed in low-gestational-age infants (<29 weeks' gestation). The data highlight the clinical signs most commonly observed in infants with NEC and thus provide NICU nurses an evidence-based guide for assessment and care of infants with NEC.Keywords
This publication has 57 references indexed in Scilit:
- 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitisThe ISME Journal, 2009
- Prolonged Duration of Initial Empirical Antibiotic Treatment Is Associated With Increased Rates of Necrotizing Enterocolitis and Death for Extremely Low Birth Weight InfantsPediatrics, 2009
- Bacterial Colonization, Probiotics, and Necrotizing EnterocolitisJournal of Clinical Gastroenterology, 2008
- Clinical Predictors of Necrotizing Enterocolitis in Premature InfantsNursing Research, 2008
- Necrotizing Enterocolitis in NewbornsDrugs, 2008
- Neurodevelopmental outcomes of neonates with medically and surgically treated necrotizing enterocolitisArchives of Disease in Childhood: Fetal & Neonatal, 2007
- Does necrotising enterocolitis impact the neurodevelopmental and growth outcomes in preterm infants with birthweight ≤1250 g?Journal of Paediatrics and Child Health, 2006
- Randomized trial of “slow” versus “fast” feed advancements on the incidence of necrotizing enterocolitis in very low birth weight infantsThe Journal of Pediatrics, 1999
- Pathology of neonatal necrotizing enterocolitis: A ten-year experienceThe Journal of Pediatrics, 1990
- Comparison of fast- and slow-feeding rate schedules to the development of necrotizing enterocolitisThe Journal of Pediatrics, 1976