Sodium 1-(12-Hydroxy)octadecanyl Sulfate, an MMP2 Inhibitor, Isolated from a Tunicate of the Family Polyclinidae
- 26 October 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 65 (12), 1936-1938
- https://doi.org/10.1021/np020250o
Abstract
Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor. 1 The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC50 value of 9.0 μg/mL.Keywords
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