Determination of monoamines in brain nuclei by high performance liquid chromatography with electrochemical detection : Young vs. middle aged rats

Abstract
A previously described high performance liquid chromatographic method for simultaneously measuring norepinephrine, dopamine, serotonin and 5-hydroxyindole acetic acid has been modified to permit analysis of the monoamines in microdissected brain nuclei from a single rat. Results of measurements in 12 nuclei of young and middle aged male rats are presented.