Selective p38α mitogen-activated protein kinase inhibitor attenuates lung inflammation and fibrosis in IL-13 transgenic mouse model of asthma
Open Access
- 1 November 2008
- journal article
- Published by Taylor & Francis Ltd in Journal of Asthma and Allergy
- Vol. 1, 31-44
- https://doi.org/10.2147/JAA.S4199
Abstract
Peer reviewed article authored by (Jing Ying Ma, Satyanarayana Medicherla, Irene Kerr, Ruban Mangadu, Andrew A Protter, Linda S Higgins). Read article or submit your manuscript for publishing.Keywords
This publication has 26 references indexed in Scilit:
- SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cellsCellular Signalling, 2007
- Transforming Growth Factor-β Receptor Type 1 (TGFβRI) Kinase Activity but Not p38 Activation Is Required for TGFβRI-Induced Myofibroblast Differentiation and Profibrotic Gene ExpressionMolecular Pharmacology, 2006
- Gadd45β is important for perpetuating cognate and inflammatory signals in T cellsNature Immunology, 2003
- A Small Molecule Very Late Antigen–4 Antagonist Can Inhibit Ovalbumin-induced Lung InflammationAmerican Journal of Respiratory and Critical Care Medicine, 2003
- The role of T lymphocytes in the pathogenesis of asthmaJournal of Allergy and Clinical Immunology, 2003
- Antigen-Independent Th2 Cell Differentiation by Stimulation of CD28: Regulation Via IL-4 Gene Expression and Mitogen-Activated Protein Kinase ActivationThe Journal of Immunology, 2001
- Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinasesBlood, 2000
- p38α Mitogen-Activated Protein Kinase Is Activated by CD28-Mediated Signaling and Is Required for IL-4 Production by Human CD4+CD45RO+ T Cells and Th2 Effector CellsThe Journal of Immunology, 1999
- Effects of Th2 Cytokines on Chemokine Expression in the Lung: IL-13 Potently Induces Eotaxin Expression by Airway Epithelial CellsThe Journal of Immunology, 1999
- “Stress-Responsive” Mitogen-Activated Protein Kinases (c-Jun N-Terminal Kinases and p38 Mitogen-Activated Protein Kinases) in the MyocardiumCirculation Research, 1998