Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes
- 17 July 2011
- journal article
- Published by Elsevier BV in European Journal of Pharmaceutical Sciences
- Vol. 43 (4), 297-307
- https://doi.org/10.1016/j.ejps.2011.05.002
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Screening of OATP1B1/3 and OCT1 inhibitors in cryopreserved hepatocytes in suspensionEuropean Journal of Pharmaceutical Sciences, 2010
- In Vitro Investigation of the Hepatobiliary Disposition Mechanisms of the Antifungal Agent Micafungin in Humans and RatsDrug Metabolism and Disposition, 2010
- Membrane transporters in drug developmentNature Reviews Drug Discovery, 2010
- Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro ModelDrug Metabolism and Disposition, 2008
- Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearanceEuropean Journal of Pharmaceutics and Biopharmaceutics, 2006
- INVOLVEMENT OF TRANSPORTERS IN THE HEPATIC UPTAKE AND BILIARY EXCRETION OF VALSARTAN, A SELECTIVE ANTAGONIST OF THE ANGIOTENSIN II AT1-RECEPTOR, IN HUMANSPublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,2006
- EXPRESSION AND INDUCTION POTENTIAL OF CYTOCHROMES P450 IN HUMAN CRYOPRESERVED HEPATOCYTESDrug Metabolism and Disposition, 2005
- EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCEDrug Metabolism and Disposition, 2004
- Multispecific amphipathic substrate transport by an organic anion transporter of human liverJournal of Hepatology, 1996
- Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.JCI Insight, 1994