Berberine in toxin‐induced experimental cholera

Abstract

Appendix on berberine in toxin-induced experimental cholera Summary 1 Oral administration of berberine to infant rabbits 18–24 h before the intraintestinal administration of choleragenic toxins, arrests diarrhoea or significantly prolongs the survival time. 2 The use of berberine in the treatment of clinical cholera is further justified. 3 Berberine is an antidiarrhoeal drug and the host tissues play a major part in the control of diarrhoeal symptoms.