p300 Is Elevated in Systemic Sclerosis and Its Expression Is Positively Regulated by TGF-β: Epigenetic Feed-Forward Amplification of Fibrosis
- 1 May 2013
- journal article
- Published by Elsevier BV in Journal of Investigative Dermatology
- Vol. 133 (5), 1302-1310
- https://doi.org/10.1038/jid.2012.479
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Egr-1 Induces a Profibrotic Injury/Repair Gene Program Associated with Systemic SclerosisPLOS ONE, 2011
- Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell LinesMolecular Cancer Therapeutics, 2011
- High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinomaJournal of Translational Medicine, 2011
- Peroxisome proliferator‐activated receptor‐γ abrogates Smad‐dependent collagen stimulation by targeting the p300 transcriptional coactivatorThe FASEB Journal, 2009
- Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γThe American Journal of Pathology, 2009
- The Early-Immediate Gene EGR-1 Is Induced by Transforming Growth Factor-β and Mediates Stimulation of Collagen Gene ExpressionPublished by Elsevier BV ,2006
- Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblastsRheumatology, 2005
- The Tumor Suppressor p53 Abrogates Smad-dependent Collagen Gene Induction in Mesenchymal CellsPublished by Elsevier BV ,2004
- FIZZ1 Stimulation of Myofibroblast DifferentiationThe American Journal of Pathology, 2004
- Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-β involves functional cooperation with p300/CBP transcriptional coactivatorsOncogene, 2000