Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production
Open Access
- 24 July 2001
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 15 (11), 1953-1962
- https://doi.org/10.1096/fj.01-0198com
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Molecular mechanisms of tumor metastasis and angiogenesis.Langenbecks Archives Of Surgery, 1999
- Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κBFEBS Letters, 1998
- Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphateScience, 1997
- Cell Migration: A Physically Integrated Molecular ProcessCell, 1996
- The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinaseCell, 1995
- Tumor Cell Interactions with the Extracellular Matrix During Invasion and MetastasisAnnual Review of Cell Biology, 1993
- Cadherins in cancer: implications for invasion and metastasisCurrent Opinion in Cell Biology, 1993
- E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.The Journal of cell biology, 1991
- Cadherin Cell Adhesion Receptors as a Morphogenetic RegulatorScience, 1991
- Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.Proceedings of the National Academy of Sciences of the United States of America, 1987