Characterization of Tn 916 S, a Tn 916 -Like Element Containing the Tetracycline Resistance Determinant tet (S)

Abstract
We have characterized a transferable tetracycline resistance (Tc r ) element from a Streptococcus intermedius isolate. The gene responsible for this resistance was identified by PCR and Southern hybridization as tet (S). Furthermore, the genetic support for this determinant was shown to be a conjugative transposon closely related to Tn 916 . This element has been designated Tn 916 S.

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