Insights into the Role of Electrostatic Forces on the Behavior of Dry Pharmaceutical Particulate Systems
- 16 May 2006
- journal article
- Published by Springer Science and Business Media LLC in Pharmaceutical Research
- Vol. 23 (5), 997-1007
- https://doi.org/10.1007/s11095-006-9934-0
Abstract
Under different charging conditions, particles can be either attracted or repulsed by each other, causing powder agglomeration or segregation. Such behavior can be detrimental in many processes aimed at achieving particulate mixture homogeneity. Consequently, the effects of electrostatic charges on mixing kinetics must be well understood to insure a high level of process control, product quality, and reproducibility.Keywords
This publication has 12 references indexed in Scilit:
- Electrostatic Effects on Dispersion, Transport, and Deposition of Fine Pharmaceutical Powders: Development of an Experimental Method for Quantitative AnalysisParticulate Science and Technology, 2002
- Quantifying electrostatic interactions in pharmaceutical solid systemsInternational Journal of Pharmaceutics, 2001
- Effect of Drug Agglomerates Upon the Kinetics of Mixing of Low Dosage Cohesive Powder MixturesDrug Development and Industrial Pharmacy, 1989
- Magnesium stearate susceptibility of directly compressible materials as an indication of fragmentation propertiesPowder Technology, 1988
- Electrostatic phenomena during powder handlingPowder Technology, 1984
- Electrostatic charge interactions in ordered powder mixesJournal of Pharmacy and Pharmacology, 1982
- Electrical Conductance of Directly Compressible Materials under PressureJournal of Pharmaceutical Sciences, 1979
- Static ElectrificationPublished by Springer Science and Business Media LLC ,1958
- The Static Electrification of Dust Particles on Dispersion into a CloudJournal of Applied Physics, 1950
- LII. On the electrification associated with dust-cloudsThe London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 1913