MRI of the thorax during whole‐body MRI: Evaluation of different MR sequences and comparison to thoracic multidetector computed tomography (MDCT)
Open Access
- 25 January 2008
- journal article
- research article
- Published by Wiley in Journal of Magnetic Resonance Imaging
- Vol. 27 (3), 538-545
- https://doi.org/10.1002/jmri.21218
Abstract
Purpose To evaluate the accuracy of four MR sequences used as part of a whole‐body MRI protocol to detect pulmonary lesions in cancer patients. Materials and Methods A total of 31 oncology patients were imaged in a 1.5T MR scanner (Magnetom Avanto; Siemens Medical Solutions, Germany) for whole‐body staging. MR chest imaging included: axial and coronal T2‐weighted (T2w)–short‐tau inversion‐recovery (STIR), axial T2w turbo spin‐echo (TSE), and contrast‐enhanced (CE) three‐dimensional (3D) volumetric interpolated breathhold examination (VIBE). Multidetector computed tomography (MDCT) of the thorax served as the reference standard. The MDCT and MR images were evaluated independently by two radiologists. Comparative analysis was performed per lesion, per lobe, and per patient. Sensitivity, specificity, and predictive values were determined. Results Compared to MDCT that detected 268 pulmonary lesions ranging from 2 to 75 mm in diameter, the MR sensitivities were 91.1%, 92.5%, 90.8%, and 87.3% for the coronal STIR, the axial STIR, the axial T2w‐TSE, and the axial CE 3D‐VIBE, respectively. Undetected pulmonary lesions were either calcified or smaller than 10 mm in the axial diameter. With coronal STIR, six false‐positive findings were detected; with axial STIR, 14 were detected; with axial T2w‐TSE, 10 were detected; and with 3D‐VIBE, seven were detected. Conclusion Pulmonary MRI is feasible as part of a whole‐body MRI protocol. In our study, STIR images achieved high accuracy compared to chest MDCT for pulmonary lesions of 3 mm in size or larger. J. Magn. Reson. Imaging 2008.Keywords
This publication has 25 references indexed in Scilit:
- Breast MRI lesion classification: Improved performance of human readers with a backpropagation neural network computer‐aided diagnosis (CAD) systemJournal of Magnetic Resonance Imaging, 2006
- Detection of Pulmonary Nodules Using a 2D HASTE MR Sequence: Comparison with MDCTAmerican Journal of Roentgenology, 2005
- A Comparison of Whole-Body MRI and CT for the Staging of LymphomaAmerican Journal of Roentgenology, 2005
- Pulmonary staging in colorectal cancer--is computerised tomography the answer?The Annals of The Royal College of Surgeons of England, 2005
- Herztumoren: Magnetresonanztomographie und Mehrschicht-Spiral-CTRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2005
- Fast Whole-Body Assessment of Metastatic Disease Using a Novel Magnetic Resonance Imaging SystemInvestigative Radiology, 2005
- Accuracy of Helical CT in the Detection of Pulmonary Metastases: Is Intraoperative Palpation Still Necessary?The Annals of Thoracic Surgery, 2004
- Pulmonary metastases: can accurate radiological evaluation avoid thoracotomic approach?European Journal of Cardio-Thoracic Surgery, 2002
- Magnetic resonance imaging of the lung with a volumetric interpolated 3D-Gradient echo sequenceRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2001