Allergy to Birch Pollen and Apple, and Gross‐Reactivity of the Allergens Studied with the RAST
- 1 June 1980
- Vol. 35 (4), 297-300
- https://doi.org/10.1111/j.1398-9995.1980.tb01770.x
Abstract
Apple-pulp allergens are unstable, but fresh material can be used for skin testing. Stable allergens, probably of a protein nature, were extracted from apple seed and used in radioallergosorbent tests (RAST). Apple-seed allergens were shown by RAST inhibition to cross-react with birch pollen allergen(s). Cross-reactivity may explain the frequent co-occurrence of birch pollen and apple allergy. Approximately 50% of patients in a group with immediate hypersensitivity to birch pollen were also sensitive to apple as judged by a history of symptoms, skin tests with apple-pulp and apple-seed preparations, and apple-seed RAST.Keywords
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