Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression
Open Access
- 30 September 2011
- journal article
- Published by Elsevier BV in Molecular Immunology
- Vol. 48 (15-16), 1800-1808
- https://doi.org/10.1016/j.molimm.2011.05.013
Abstract
No abstract availableKeywords
Funding Information
- Wellcome Trust
This publication has 49 references indexed in Scilit:
- Comparative Study of the Ability ofLeishmania mexicanaPromastigotes and Amastigotes To Alter Macrophage Signaling and FunctionsInfection and Immunity, 2010
- Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogensNature Immunology, 2008
- Leishmania initially activates but subsequently down-regulates intracellular mitogen-activated protein kinases and nuclear factor-κB signaling in macrophagesMolecular Immunology, 2008
- Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-relFree Radical Biology & Medicine, 2007
- Leishmania lipophosphoglycan activates the transcription factor activating protein 1 in J774A.1 macrophages through the extracellular signal-related kinase (ERK) and p38 mitogen-activated protein kinaseMolecular and Biochemical Parasitology, 2005
- Inhibition of Lipopolysaccharide-Induced Macrophage IL-12 Production byLeishmania mexicanaAmastigotes: The Role of Cysteine Peptidases and the NF-κB Signaling PathwayThe Journal of Immunology, 2004
- MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll‐like receptor 2 signalingEuropean Journal of Immunology, 2003
- Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2Molecular and Biochemical Parasitology, 2003
- Determination of arginase activity in macrophages: a micromethodJournal of Immunological Methods, 1994
- Experimental cutaneous leishmaniasis. II. A possible role for prostaglandins in exacerbation of disease in Leishmania major-infected BALB/c mice.The Journal of Immunology, 1987