HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging
- 23 August 2010
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 46 (36), 6684-6686
- https://doi.org/10.1039/c0cc01041c
Abstract
We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.Keywords
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