Correlation of rhinoscopic signs of inflammation with histologic findings in nasal biopsy specimens of cats with or without upper respiratory tract disease
- 1 August 2004
- journal article
- research article
- Published by American Veterinary Medical Association (AVMA) in Journal of the American Veterinary Medical Association
- Vol. 225 (3), 395-400
- https://doi.org/10.2460/javma.2004.225.395
Abstract
Objective—To investigate the correlation of cumulative rhinoscopic findings of hyperemia, mucus accumulation, and turbinate destruction with the type and severity of inflammatory infiltrates in nasal biopsy specimens of cats with or without upper respiratory tract disease. Design—Prospective study. Animals—Cats with (n = 11) and without (6) upper respiratory tract disease and cats with unknown medical histories (27). Procedures—Lesions of hyperemia, mucus accumulation, and turbinate destruction detected rhinoscopically were each scored (scale, 0 [absent] to 3 [severe]), and a cumulative rhinoscopic score for each nasal cavity was calculated. Fifty biopsy specimens were examined histologically, and inflammatory infiltrates (lymphoplasmacytic or neutrophilic) were graded as absent, mild, moderate, or severe. Cumulative rhinoscopic scores and inflammation grades were compared for each specimen-cavity combination. Results—In cats of known disease status, there was a positive but weak correlation between cumulative rhinoscopic scores and inflammation grades in biopsy specimens. In cats of unknown disease status, there was no similar correlation. Biopsy specimens with minimal inflammation were commonly obtained from nasal cavities with low rhinoscopic scores; specimens with moderate or severe inflammatory changes were frequently obtained from cavities that appeared normal rhinoscopically. Type of inflammatory infiltrates was not correlated with rhinoscopic signs of inflammation. Conclusions and Clinical Relevance—The correlation of rhinoscopic findings with inflammation severity in nasal biopsy specimens (determined histologically) was weak or lacking in cats of known and unknown disease status, respectively. Results indicated that rhinoscopy with biopsy provides more complete evaluation of nasal disease than rhinoscopy alone in cats. ( J Am Vet Med Assoc 2004;225: 395–400)Keywords
This publication has 14 references indexed in Scilit:
- Idiopathic lymphoplasmacytic rhinitis in dogs: 37 cases (1997–2002)Journal of the American Veterinary Medical Association, 2004
- A retrospective study of non-specific rhinitis in 22 cats and the value of nasal cytology and histopathologyJournal of Feline Medicine and Surgery, 2003
- The Significance of Routine Duodenal Biopsies in Pediatric Patients Undergoing Upper Intestinal EndoscopyJournal of Clinical Gastroenterology, 2003
- Clinical and histopathological changes of the nasal mucosa induced by occupational exposure to sulphuric acid mistsOccupational and Environmental Medicine, 2003
- Microscopic ColitisMayo Clinic Proceedings, 2003
- Fungal rhinitis and sinusitis in three catsJournal of the American Veterinary Medical Association, 2003
- Routine colonic mucosal biopsy and ileoscopy increases diagnostic yield in patients undergoing colonoscopy for diarrheaJournal of Gastroenterology and Hepatology, 2002
- Rhinoscopy, Pharyngoscopy, and LaryngoscopyVeterinary Clinics of North America: Small Animal Practice, 2001
- Evaluation of brush cytology in the diagnosis of chronic intranasal disease in catsJournal of Small Animal Practice, 1998
- Comparisons between endoscopic and histologic evaluation of the gastrointestinal tract in dogs and cats: 75 cases (1984–1987)Journal of the American Veterinary Medical Association, 1990