Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice
- 15 November 2010
- journal article
- research article
- Published by Elsevier BV in Free Radical Biology & Medicine
- Vol. 49 (9), 1406-1416
- https://doi.org/10.1016/j.freeradbiomed.2010.07.026
Abstract
No abstract availableKeywords
This publication has 72 references indexed in Scilit:
- The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse modelJournal of Hepatology, 2008
- Resveratrol alleviates alcoholic fatty liver in miceAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2008
- Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in miceHepatology, 2007
- Thioredoxin and TRAF Family Proteins Regulate Reactive Oxygen Species-Dependent Activation of ASK1 through Reciprocal Modulation of the N-Terminal Homophilic Interaction of ASK1Molecular and Cellular Biology, 2007
- Diallyl sulfide induces heme oxygenase-1 through MAPK pathwayArchives of Biochemistry and Biophysics, 2004
- Chronic Ethanol Exposure Potentiates Lipopolysaccharide Liver Injury Despite Inhibiting Jun N-terminal Kinase and Caspase 3 ActivationPublished by Elsevier BV ,2002
- Regulation of peroxisome proliferator activated receptor α-mediated pathways in alcohol fed cytochrome P450 2E1 deficient miceHepatology Research, 2001
- Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the ratHepatology, 1997
- Gadolinium chloride reduces cytochrome P450: Relevance to chemical-induced hepatotoxicityToxicology, 1997
- Apoptosis and Bcl‐2 Protein Expression in Experimental Alcoholic Liver Disease in the RatAlcohol: Clinical and Experimental Research, 1995