A CONTROLLED CLINICOPATHOLOGICAL STUDY OF MYOCARDIAL FIBROSIS IN SYSTEMIC-SCLEROSIS (SCLERODERMA)
- 1 May 1990
- journal article
- research article
- Vol. 17 (5), 656-662
Abstract
Clinicopathologic correlations of myocardial fibrosis were examined in 54 autopsied patients with scleroderma and 54 age and sex matched autopsy controls. Thirty eight (70%) of the patients with scleroderma had myocardial fibrosis compared to 20 (37%) of the controls (p < 0.005). There was no significant difference in the prevalence of contraction band necrosis in the patients with scleroderma (22%) compared to controls (17%). Patients with scleroderma with left ventricular dysfunction in the absence of other causative factors clinically had a greater prevalence of both advanced myocardial fibrosis (60%) and contraction band necrosis (40%) than did the other patients with scleroderma with the greatest likelihood of advanced myocardial fibrosis can be dentified clinically, and their findings are consistent with the presence of microvascular coronary vasospasm, a "myocardial Raynaud''s phenomenon.".This publication has 7 references indexed in Scilit:
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