Posterior Reversible Encephalopathy Syndrome During Ipilimumab Therapy for Malignant Melanoma
- 20 February 2012
- journal article
- diagnosis in-oncology
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 30 (6), e76-e78
- https://doi.org/10.1200/jco.2011.38.7886
Abstract
.....T his is the first case of PRES during ipilimumab therapy. Increasing awareness of PRES is needed in patients who undergo anti–CTLA-4 therapies and develop irAEs such as hypophysitis in our patient. Autoimmune disorders are associated with an increased risk of PRES; autoimmune hypophysitis, however, does not seem to be implicated in the development of PRES. Further inves-\ud tigations on the mechanisms of toxicity and risk factors for PRES are necessarKeywords
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