Liver-Related Deaths in Persons Infected With the Human Immunodeficiency Virus

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Abstract
Mortality among human immunodeficiency virus (HIV)–infected persons living in resource-rich countries has declined from 20 to 30 per 100 person-years before 1995, when combination antiretroviral therapy (cART) became available, to 2 to 5 per 100 person-years in recent years.1,2 Nevertheless, mortality rates remain high relative to uninfected persons, even in settings with access to therapy.3-5 The risk of death from AIDS may be related to therapeutic failure,6 late initiation of cART,7 interruption or refusal of cART, incomplete adherence, or drug resistance.