Long-term persistence and effects of fetal microchimerisms on disease onset and status in a cohort of women with rheumatoid arthritis and systemic lupus erythematosus
Open Access
- 18 November 2013
- journal article
- Published by Springer Science and Business Media LLC in BMC Musculoskeletal Disorders
- Vol. 14 (1), 325
- https://doi.org/10.1186/1471-2474-14-325
Abstract
The discovery of a fetal cells transfer to the mother is a phenomenon with multiple implications for autoimmunity and tolerance. The prevalence and meaning of the feto-maternal microchimerism (MC) in rheumatic diseases has not been thoroughly investigated. The aim of this study was to analyze the prevalence of fetal MC in patients with inflammatory rheumatic diseases and to investigate the association of MC with disease onset and current status.Keywords
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