A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells
- 4 August 2006
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 346 (3), 707-720
- https://doi.org/10.1016/j.bbrc.2006.05.164
Abstract
No abstract availableKeywords
This publication has 58 references indexed in Scilit:
- Exploiting the PI3K/AKT Pathway for Cancer Drug DiscoveryNature Reviews Drug Discovery, 2005
- Simple and efficient DNA vector-based RNAi systems in mammalian cellsBiochemical and Biophysical Research Communications, 2005
- Synthetic shRNAs as potent RNAi triggersNature Biotechnology, 2004
- Unlocking the potential of the human genome with RNA interferenceNature, 2004
- siRNAs: applications in functional genomics and potential as therapeuticsNature Reviews Drug Discovery, 2004
- A resource for large-scale RNA-interference-based screens in mammalsNature, 2004
- Approaches for the sequence-specific knockdown of mRNANature Biotechnology, 2003
- Killing the messenger: short RNAs that silence gene expressionNature Reviews Molecular Cell Biology, 2003
- Effective expression of small interfering RNA in human cellsNature Biotechnology, 2002
- U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cellsNature Biotechnology, 2002