Nitrogen-Doped Graphene and Its Application in Electrochemical Biosensing
Top Cited Papers
- 7 April 2010
- journal article
- Published by American Chemical Society (ACS) in ACS Nano
- Vol. 4 (4), 1790-1798
- https://doi.org/10.1021/nn100315s
Abstract
Chemical doping with foreign atoms is an effective method to intrinsically modify the properties of host materials. Among them, nitrogen doping plays a critical role in regulating the electronic properties of carbon materials. Recently, graphene, as a true two-dimensional carbon material, has shown fascinating applications in bioelectronics and biosensors. In this paper, we report a facile strategy to prepare N-doped graphene by using nitrogen plasma treatment of graphene synthesized via a chemical method. Meanwhile, a possible schematic diagram has been proposed to detail the structure of N-doped graphene. By controlling the exposure time, the N percentage in host graphene can be regulated, ranging from 0.11 to 1.35%. Moreover, the as-prepared N-doped graphene has displayed high electrocatalytic activity for reduction of hydrogen peroxide and fast direct electron transfer kinetics for glucose oxidase. The N-doped graphene has further been used for glucose biosensing with concentrations as low as 0.01 mM in the presence of interferences.Keywords
This publication has 52 references indexed in Scilit:
- Graphene Based Electrochemical Sensors and Biosensors: A ReviewElectroanalysis, 2010
- Graphene Oxide Amplified Electrogenerated Chemiluminescence of Quantum Dots and Its Selective Sensing for Glutathione from Thiol-Containing CompoundsAnalytical Chemistry, 2009
- Aqueous Stabilization and Self‐Assembly of Graphene Sheets into Layered Bio‐Nanocomposites using DNAAdvanced Materials, 2009
- Spin Gapless Semiconductor−Metal−Half-Metal Properties in Nitrogen-Doped Zigzag Graphene NanoribbonsACS Nano, 2009
- Electrochemical Sensing and Biosensing Platform Based on Chemically Reduced Graphene OxideAnalytical Chemistry, 2009
- A Graphene Platform for Sensing BiomoleculesAngewandte Chemie-International Edition, 2009
- Direct Electrochemistry of Glucose Oxidase and Biosensing for Glucose Based on GrapheneAnalytical Chemistry, 2009
- Graphene-Based Single-Bacterium Resolution Biodevice and DNA Transistor: Interfacing Graphene Derivatives with Nanoscale and Microscale BiocomponentsNano Letters, 2008
- Highly conducting graphene sheets and Langmuir–Blodgett filmsNature Nanotechnology, 2008
- The rise of grapheneNature Materials, 2007