Heart rate variability in menopausal hot flashes during sleep
- 1 August 2011
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Menopause
- Vol. 18 (8), 897-900
- https://doi.org/10.1097/gme.0b013e31820ac941
Abstract
Objective: The aim of this study was to determine if heart rate variability changes during hot flashes recorded during sleep. Methods: This study was performed in a university medical center laboratory with 16 postmenopausal women demonstrating at least four hot flashes per night. Polysomnography, heart rate, and sternal skin conductance to indicate hot flashes were recorded in controlled, laboratory conditions. ResultsL: For the frequency bin of 0 to 0.15 Hz, spectral power was greater during waking compared with non-rapid eye movement sleep and less during stages 3 and 4 compared with stages 1 and 2. Power was greater during hot flashes compared with subsequent periods for all hot flashes. Power was greater during hot flashes compared with preceding and subsequent periods for those recorded during stage 1 sleep. For waking hot flashes, power in this band was higher before hot flashes than during or after them. Conclusions: These data are consistent with our theory of elevated sympathetic activation as a trigger for menopausal hot flashes and with previous work on heart rate variability during the stages of sleep.Keywords
This publication has 14 references indexed in Scilit:
- Hot flashes and cardiac vagal controlMenopause, 2010
- Association between vasomotor hot flashes and heart rate variability in recently postmenopausal womenMenopause, 2010
- Autonomic effects on the spectral analysis of heart rate variability after exerciseAmerican Journal of Physiology-Heart and Circulatory Physiology, 2009
- Sleep disturbance in menopauseMenopause, 2007
- Evaluation of Four Proposed Bleeding Criteria for the Onset of Late Menopausal TransitionJournal of Clinical Endocrinology & Metabolism, 2006
- Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in humansNeuroscience Letters, 2002
- Heart Rate VariabilityCirculation, 1996
- Regional origins of 3-methoxy-4-hydroxyphenylglycol in plasma: effects of chronic sympathetic nervous activation and denervation, and acute reflex sympathetic stimulationJournal of the Autonomic Nervous System, 1995
- Continuous 24-hour assessment of the neural regulation of systemic arterial pressure and RR variabilities in ambulant subjects.Circulation, 1990
- Laboratory and Ambulatory Monitoring of Menopausal Hot FlashesPsychophysiology, 1989