Transfer of specificity by murine α and β T-cell receptor genes
- 1 March 1986
- journal article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 320 (6059), 232-238
- https://doi.org/10.1038/320232a0
Abstract
T-cell receptor alpha- and beta-chain genes were isolated from a class I major histocompatibility complex-restricted cytotoxic T-cell clone and transferred by protoplast fusion into another cytolytic T-cell clone of different specificity. Expression of the transfected alpha and beta genes endowed the recipient cell with the specificity of the donor cell.Keywords
This publication has 53 references indexed in Scilit:
- Role of L3T4 in antigen-driven activation of a class I-specific T cell hybridoma.The Journal of Experimental Medicine, 1985
- Molecular Genetics of the T Cell-Receptor Beta ChainAnnual Review of Immunology, 1985
- T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility ComplexAnnual Review of Immunology, 1985
- Identification of antigen receptor-associated structures on murine T cellsNature, 1985
- The T3/T cell receptor complex: antigenic distinction between the two 20-kd T3 (T3-delta and T3-epsilon) subunits.The EMBO Journal, 1985
- Biochemistry and Distribution of the T Cell ReceptorImmunological Reviews, 1984
- Genes Encoding the Human T Cell Antigen ReceptorImmunological Reviews, 1984
- The Human T-Cell ReceptorAnnual Review of Immunology, 1984
- The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.The Journal of Experimental Medicine, 1983
- Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen ReceptorsImmunological Reviews, 1982