Childhood neuropsychological deficits associated with adult obsessive–compulsive disorder
Open Access
- 1 August 2009
- journal article
- research article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 195 (2), 138-141
- https://doi.org/10.1192/bjp.bp.108.056812
Abstract
Background: Existing neuropsychological studies of obsessive–compulsive disorder (OCD) are cross-sectional and do not provide evidence of whether deficits are trait-related (antecedent and independent of symptomatology) or state-related (a consequence, dependent on symptomatology).Aims: To investigate whether there are premorbid neuropsychological deficits associated with adult OCD.Method: Longitudinal data were collected from participants of the Dunedin Multidisciplinary Health and Developmental study. Neuropsychological data collected at age 13 were linked with age 32 diagnosis of OCD.Results: The group who had OCD at age 32 differed significantly from the control group with no OCD on their performance at age 13 on neuropsychological tests of visuospatial, visuoconstructive and visuomotor skills, controlling for gender and socioeconomic status, but did not differ on tests of general IQ or verbal ability. Performance of the group with OCD on tests of executive functioning was mixed.Conclusions: Individuals with OCD have premorbid impairment in visuospatial abilities and some forms of executive functioning, consistent with biological models of OCD.Keywords
This publication has 17 references indexed in Scilit:
- Are there reliable neuropsychological deficits in obsessive–compulsive disorder?Journal of Psychiatric Research, 2006
- The Changing Prevalence and Severity of Obsessive-Compulsive Disorder Criteria From DSM-III to DSM-IVAmerican Journal of Psychiatry, 2005
- Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample.Journal of Abnormal Psychology, 2001
- Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample.Journal of Abnormal Psychology, 2001
- Is there sexual dimorphism in obsessive-compulsive disorder?Neuroscience & Biobehavioral Reviews, 1999
- Toward a Neurodevelopmental Model of Obsessive–Compulsive DisorderBiological Psychiatry, 1998
- Psychiatric disorder in a birth cohort of young adults: Prevalence, comorbidity, clinical significance, and new case incidence from ages 11 to 21.Journal of Consulting and Clinical Psychology, 1996
- Neuropsychological correlates of psychopathology in an unselected cohort of young adolescents.Journal of Abnormal Psychology, 1989
- Neuropsychological correlates of psychopathology in an unselected cohort of young adolescents.Journal of Abnormal Psychology, 1989
- Factor analysis of the WISC-R at 11 age levels between 61/2 and 161/2 years.Journal of Consulting and Clinical Psychology, 1975