Neuropathy in two cobalamin-deficient breast-fed infants of vegetarian mothers

Abstract

We describe the electrophysiological findings in 2 infants with deficient cobalamin intake. After normal development, psychomotor regression appeared after the 6th month, leading to severe hypotonia and apathy before the 12th month. Electrodiagnostic evaluation showed sensory neuropathy in both cases, associated with motor neuropathy in 1 case. Thus, in an acquired floppy infant syndrome, electrophysiological signs of peripheral neuropathy contributed to the diagnosis of a curable metabolic disorder. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 252–254, 1999