Memory for Semantically Related and Unrelated Declarative Information: The Benefit of Sleep, the Cost of Wake
Open Access
- 22 March 2012
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (3), e33079
- https://doi.org/10.1371/journal.pone.0033079
Abstract
Numerous studies have examined sleep's influence on a range of hippocampus-dependent declarative memory tasks, from text learning to spatial navigation. In this study, we examined the impact of sleep, wake, and time-of-day influences on the processing of declarative information with strong semantic links (semantically related word pairs) and information requiring the formation of novel associations (unrelated word pairs). Participants encoded a set of related or unrelated word pairs at either 9am or 9pm, and were then tested after an interval of 30 min, 12 hr, or 24 hr. The time of day at which subjects were trained had no effect on training performance or initial memory of either word pair type. At 12 hr retest, memory overall was superior following a night of sleep compared to a day of wakefulness. However, this performance difference was a result of a pronounced deterioration in memory for unrelated word pairs across wake; there was no sleep-wake difference for related word pairs. At 24 hr retest, with all subjects having received both a full night of sleep and a full day of wakefulness, we found that memory was superior when sleep occurred shortly after learning rather than following a full day of wakefulness. Lastly, we present evidence that the rate of deterioration across wakefulness was significantly diminished when a night of sleep preceded the wake period compared to when no sleep preceded wake, suggesting that sleep served to stabilize the memories against the deleterious effects of subsequent wakefulness. Overall, our results demonstrate that 1) the impact of 12 hr of waking interference on memory retention is strongly determined by word-pair type, 2) sleep is most beneficial to memory 24 hr later if it occurs shortly after learning, and 3) sleep does in fact stabilize declarative memories, diminishing the negative impact of subsequent wakefulness.Keywords
This publication has 32 references indexed in Scilit:
- An opportunistic theory of cellular and systems consolidationTrends in Neurosciences, 2011
- The Role of Sleep in Directed Forgetting and Remembering of Human MemoriesCerebral Cortex, 2011
- Sleep Contributes to the Strengthening of Some Memories Over Others, Depending on Hippocampal Activity at LearningJournal of Neuroscience, 2011
- Sleep’s role in the processing of unwanted memoriesJournal of Sleep Research, 2010
- Learning by observation requires an early sleep windowProceedings of the National Academy of Sciences of the United States of America, 2009
- The role of sleep in false memory formationNeurobiology of Learning and Memory, 2009
- The contribution of sleep to hippocampus-dependent memory consolidationTrends in Cognitive Sciences, 2007
- The Psychology and Neuroscience of ForgettingAnnual Review of Psychology, 2004
- The Beneficial Effect of Sleep in an Extended Jenkins and Dallenbach ParadigmPsychophysiology, 1977
- Sleep and Memory: Retention 8 and 24 Hours After Initial LearningPsychophysiology, 1975