Surgery for medically intractable epilepsy due to postinfectious etiologies
Open Access
- 1 June 2010
- Vol. 51 (6), 1097-1100
- https://doi.org/10.1111/j.1528-1167.2010.02538.x
Abstract
Medically intractable epilepsy (MIE) resulting from postinfectious etiologies requiring surgery have been uncommonly reported. A series of 28 cases are presented (hospital prevalence 5.7%). The mean duration of epilepsy prior to surgery was 8.2 ± 2.1 years. The mean time of onset of epilepsy after central nervous system infection was 1.4 ± 0.9 years (range 0–19 years). The pathologies included postpyogenic meningitic/encephalitic sequel (8), neurocysticercosis (6), tuberculomas/posttuberculous etiology (4), postpyogenic abscess of otogenic etiology (4), posttraumatic abscess–related gliosis (2), and gliosis of unknown infectious etiology (4) cases. Surgery included mesial temporal (11), lateral temporal (4), frontal (9), parietal (2) resections and hemispherotomy (1). Hippocampal sclerosis was seen in nine cases (4 neurocysticercosis) and this occurred in younger persons as compared to neocortical epilepsies. Good outcome (Engel class I and II) was seen in 23 of 28 cases (Engel class I in 17).Keywords
This publication has 11 references indexed in Scilit:
- Surgical outcome of cortical dysplasias presenting with chronic intractable epilepsy: A 10-year experienceNeurology India, 2008
- Hippocampal sclerosis in association with neurocysticercosisEpileptic Disorders, 2007
- Presurgical evaluation in refractory epilepsy secondary to meningitis or encephalitis: bilateral memory deficits often preclude surgeryEpileptic Disorders, 2007
- Neurocysticercosis and microscopic hippocampal dysplasia in a patient with refractory mesial temporal lobe epilepsyArquivos de Neuro-Psiquiatria, 2006
- Neurocysticercosis, mesial temporal lobe epilepsy, and hippocampal sclerosis: an association largely ignoredThe Lancet Neurology, 2006
- Prognosis for seizure recurrence in patients with newly diagnosed neurocysticercosisNeurology, 2002
- Experiences of epilepsy surgery in intractable seizures with past history of CNS infectionYonsei Medical Journal, 1997
- Epilepsy following brain abscess. The evaluation of possible risk factors with emphasis on new concept of epileptic focus formationActa Neurochirurgica, 1991
- The risk of unprovoked seizures after encephalitis and meningitisNeurology, 1988
- Seizures in bacterial meningitis: Prevalence, patterns, pathogenesis, and prognosisPediatric Neurology, 1985