Decreased VEGF concentration in lung tissue and vascular injury during ARDS

Open Access

1 January 2005

journal article
research article
Published by European Respiratory Society (ERS) in European Respiratory Journal

Vol. 25 (1), 139-146
https://doi.org/10.1183/09031936.04.00065504

Abstract

Endothelial injury is an important prognostic factor in acute respiratory distress syndrome (ARDS). Decreased production of vascular endothelial growth factor (VEGF) in ARDS may favour vascular lesions, since VEGF promotes endothelial survival by inhibiting apoptosis.

Keywords

ENDOTHELIAL APOPTOSIS
LUNG TISSUE
ALVEOLAR TYPE II CELLS
VASCULAR ENDOTHELIAL GROWTH FACTOR
ENDOTHELIAL CELL
TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE

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