Echocardiographic measurements in normal subjects: Evaluation of an adult population without clinically apparent heart disease
- 1 December 1979
- journal article
- research article
- Published by Wiley in Journal of Clinical Ultrasound
- Vol. 7 (6), 439-447
- https://doi.org/10.1002/jcu.1870070606
Abstract
In order to determine normal echocardiographic values for older subjects, we studied 136 adults (78 men and 58 women, 20 to 97 years of age) without evidence of cardiovascular disease. When patients were subdivided into six age groups, progressive changes were found in mean normal values for various parameters. Specifically, when the oldest group (over 70 years) was compared with the youngest group (21–30 years), significant (p < 0.01) increases in aortic root (22 percent) and left atrial (16 percent) dimensions, in ventricular septal (20 percent) and left ventricular free-wall (18 percent) thicknesses, and in estimated left ventricular mass (15 percent) were noted. In addition, a significant (p < 0.01) decrease in mean mitral E-F slope (43 percent) and slight decreases in mean left ventricular systolic and diastolic internal dimensions (5 and 6 percent, respectively; p < 0.05) were noted. Left ventricular ejection fraction and percentage fractional shortening were found to be independent of age. These data have been used to derive regression equations that are related to both age and body surface area. The regression equations can be used to calculate mean normal values and 95 percent prediction intervals for echocardiographic measurements in adults.Keywords
This publication has 25 references indexed in Scilit:
- Echocardiographic measurements in normal subjects. Growth-related changes that occur between infancy and early adulthood.Circulation, 1978
- Echocardiographic assessment of a normal adult aging population.Circulation, 1977
- Echocardiographic observations in patients with systemic infiltrative disease involving the heartThe American Journal of Cardiology, 1977
- Age-related changes in size of the aortic valve annulus in manAmerican Heart Journal, 1975
- Measurement of Left Ventricular Wall Thickness and Mass by EchocardiographyCirculation, 1972
- Determination of Left Ventricular Volumes by UltrasoundCirculation, 1971
- Ultrasonic Cardiac Echography for Determining Stroke Volume and Valvular RegurgitationCirculation, 1970
- A Method for Determining Left Ventricular Mass in ManCirculation, 1964
- Studies on the Central Circulation at Rest and during Exercise in the Supine and Sitting Body Position in Old MenActa Medica Scandinavica, 1961
- Changes in Cardiac Output with AgeCirculation, 1955