We examined sustained attention in 32 schizotypic and 43 normal control subjects from a large, randomly ascertained nonclinical university population. Schizotypy status was determined with the Perceptual Aberration Scale. Sustained attention was measured with the Continuous Performance Test-Identical Pairs. Schizotypic subjects displayed significantly poorer sustained-attention performance than did control subjects, as measured by d and overall hit rate. Although schizotypic subjects evidenced greater levels of anxiety and depression, sustained-attention performance was not significantly associated with these mental state factors. Our results provide evidence for a subtle sustained-attention deficit among schizotypes and are interpreted in light of previous attention research with actual schizophrenic patients as well as children at risk for schizophrenia. Utility of the psychometric high-risk strategy in psychopathology research is discussed.